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Vaccine Detail
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mRNA tumor antigen DC vaccine |
| Vaccine Information |
- Vaccine Name: mRNA tumor antigen DC vaccine
- Target Pathogen: Cancer
- Target Disease: Cancer
- Type: whole cell cancer vaccine
- Status: Clinical trial
- Host Species for Licensed Use: None
- Antigen: tumor antigen (NCT02808416)
- Immunization Route: Other
- Description: Brain metastases (BM) patients will undergo tumor resection or biopsy and the tumor tissues will be analyzed for the expression of tumor antigens and immune-related genes. Patients will then be immunized with dendritic cells (DCs) pulsed with mRNA encoded tumor antigens. These personalized cell vaccines may lead to antitumor specific T cell responses. (NCT02808416)
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| Host Response |
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| References |
NCT02808416: Personalized Cellular Vaccine for Brain Metastases (PERCELLVAC3) (PerCellVac3) [https://clinicaltrials.gov/study/NCT02808416]
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