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Vaccine Detail

Allogeneic GM-CSF-secreting Lethally Irradiated Pancreatic Tumor Cell Vaccine
Vaccine Information
  • Vaccine Name: Allogeneic GM-CSF-secreting Lethally Irradiated Pancreatic Tumor Cell Vaccine
  • Target Pathogen: Cancer
  • Target Disease: Cancer
  • Type: Live, attenuated vaccine
  • Status: Clinical trial
  • Host Species for Licensed Use: None
  • Antigen: GM-CSF (NCT00836407)
  • Immunization Route: Intradermal injection (i.d.)
  • Description: Allogeneic pancreatic tumor cells are transfected with a GM-CSF gene to treat ocally advanced, unresectable or metastatic pancreatic adenocarcinoma. It may be in combination with Ipilimumab (an antibody that blocks negative signals to T cells). (NCT00836407)
Host Response
References
NCT00836407: Ipilimumab +/​- Vaccine Therapy in Treating Patients With Locally Advanced, Unresectable or Metastatic Pancreatic Cancer [https://clinicaltrials.gov/study/NCT00836407]