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Vaccine Detail

Autologous, DNP-Modified Ovarian Cancer Vaccine
Vaccine Information
  • Vaccine Name: Autologous, DNP-Modified Ovarian Cancer Vaccine
  • Target Pathogen: Cancer
  • Target Disease: Cancer
  • Type: Live, attenuated vaccine
  • Status: Clinical trial
  • Host Species for Licensed Use: None
  • Immunization Route: Intradermal injection (i.d.)
  • Description: A vaccine made from the patient's own tumor tissue may stimulate an immune response against the patient's tumor cells. O-Vax nay induce a DTH response to autologous, DNP-modified ovarian cancer cells. The vaccine includes DNP-modified autologous ovarian tumor cells followed by cyclophosphamide then weekly doses of DNP-modified autologous ovarian tumor cells mixed with Bacillus of Calmette and Guérin (BCG). (NCT00660101)
Host Response
References
NCT00660101: Trial of Autologous, Hapten-Modified Vaccine, OVAX, in Patients With Relapsed Stage III or IV Ovarian Cancer [https://clinicaltrials.gov/study/NCT00660101]