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Vaccine Detail

OCDC and NeoDC Vaccine
Vaccine Information
  • Vaccine Name: OCDC and NeoDC Vaccine
  • Target Pathogen: Cancer
  • Target Disease: Cancer
  • Type: whole cell cancer vaccine
  • Status: Clinical trial
  • Host Species for Licensed Use: None
  • Antigen: personal neoantigen (NCT05317325)
  • Immunization Route: subcutaneous injection
  • Description: Autologous DCs are pulsed with HOCl-oxidized autologous tumor lysate (OCDC) and administered in prime phase, and a personal neoantigen-sensitized DC(NeoDC) vaccine is administered in the boost phase for Esophageal Squamous Cell Carcinoma. (NCT05317325)
Host Response
References
NCT05317325: A Translational Study of Tumor Antigen-pulsed DC Vaccine for ESCC [https://clinicaltrials.gov/study/NCT05317325]