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Vaccine Detail

Neoantigen DNA Vaccine
Vaccine Information
  • Vaccine Name: Neoantigen DNA Vaccine
  • Target Pathogen: Cancer
  • Target Disease: Cancer
  • Type: DNA vaccine
  • Status: Clinical trial
  • Host Species for Licensed Use: None
  • Antigen: neoantigen (NCT03598816)
  • Immunization Route: Intramuscular injection (i.m.)
  • Description: Personalized neoantigen DNA vaccine may enhance anti-tumor immune response in Renal Cell Carcinoma in combination with checkpoint inhibitors ipilimumab (anti-CTLA-4 antibody) and nivolumab (anti-PD-1 antibody). (NCT03598816)
Host Response
References
NCT03598816: PolyImmune {Durvalumab (MEDI4736) and Tremelimumab} & Vaccine Orchestrated Treatment for Patients With Advanced/​Metastatic Renal Cell Carcinoma (PIVOT-RCC) [https://clinicaltrials.gov/study/NCT03598816]