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Vaccine Detail

Bcr-Abl (b3a2)-Derived Peptide Vaccine
Vaccine Information
  • Vaccine Name: Bcr-Abl (b3a2)-Derived Peptide Vaccine
  • Target Pathogen: Cancer
  • Target Disease: Cancer
  • Type: Subunit vaccine
  • Status: Clinical trial
  • Host Species for Licensed Use: None
  • Antigen: bcr-abl p210-b3a2 breakpoint-derived pentapeptide (NCT00466726)
  • Immunization Route: subcutaneous injection
  • Description: The bcr-abl p210-b3a2 breakpoint-derived pentapeptide vaccine is used in combination with GM-CSF. The peptides may help the body build an effective immune response to kill cancer cells, and the GM-CSF may increase the number of immune cells found in bone marrow or peripheral blood. This combination is used to treat patients with Philadelphia chromosome-positive chronic myelogenous leukemia. (NCT00466726)
Host Response
References
NCT00466726: Vaccine Therapy in Treating Patients With Philadelphia Chromosome-Positive Chronic Myelogenous Leukemia (CML0206) [https://clinicaltrials.gov/study/NCT00466726]