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Vaccine Detail
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Autologous Total Tumor mRNA and CMV-pp65-flLAMP mRNA Loaded Liposome Vaccine |
| Vaccine Information |
- Vaccine Name: Autologous Total Tumor mRNA and CMV-pp65-flLAMP mRNA Loaded Liposome Vaccine
- Target Pathogen: Cancer
- Target Disease: Cancer
- Type: RNA
- Status: Clinical trial
- Host Species for Licensed Use: None
- Antigen: pp65 full length (fl) lysosomal associated membrane protein (LAMP) (NCT04573140)
- Immunization Route: Intravenous injection (i.v.)
- Description: Autologous total tumor mRNA and pp65 full length (fl) lysosomal associated membrane protein (LAMP) mRNA loaded DOTAP liposome vaccine is used to treat patients with Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM). (NCT04573140)
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| Host Response |
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| References |
NCT04573140: A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM) (PNOC020) [https://clinicaltrials.gov/study/NCT04573140]
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