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Vaccine Detail

Autologous Neuroblastoma Vaccine
Vaccine Information
  • Vaccine Name: Autologous Neuroblastoma Vaccine
  • Target Pathogen: Cancer
  • Target Disease: Cancer
  • Type: Live, attenuated vaccine
  • Status: Clinical trial
  • Host Species for Licensed Use: None
  • Antigen: interleukin-2 (IL-2) (NCT00048386)
  • Immunization Route: subcutaneous injection
  • Description: This vaccine uses autologous neuroblastoma cells, irradiated and genetically modified by adenoviral vectors to secrete interleukin-2 (IL-2) for patients with high-risk neuroblastoma. The adenoviral vector are used to transduce the cells ex-vivo, patients are not treated with the viral vector. (NCT00048386)
Host Response
References
NCT00048386: Neuroblastoma Vaccine for Treatment of High-Risk Neuroblastoma After Chemotherapy (CYCHE2) [https://clinicaltrials.gov/study/NCT00048386]