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Vaccine Detail

Anti-HER2/HER3 Dendritic Cell Vaccine
Vaccine Information
  • Vaccine Name: Anti-HER2/HER3 Dendritic Cell Vaccine
  • Target Pathogen: Cancer
  • Target Disease: Cancer
  • Type: Recombinant vector vaccine
  • Status: Clinical trial
  • Host Species for Licensed Use: None
  • Antigen: HER2/HER3 (NCT04348747)
  • Immunization Route: Intradermal injection (i.d.)
  • Description: The vaccine uses anti-HER2/HER3 dendritic cells in combination with Pembrolizumab in patients with Asymptomatic Brain Metastasis From Triple Negative Breast Cancer (TNBC) or HER2+ Breast Cancer (HER2+BC). The dendritic cells boost the immune system, and the Pembrolizumab enhances cancer immune responses, in combination they may shrink the cancer. (NCT04348747)
Host Response
References
NCT04348747: Dendritic Cell Vaccines Against Her2/​Her3 and Pembrolizumab for the Treatment of Brain Metastasis From Triple Negative Breast Cancer or HER2+ Breast Cancer [https://clinicaltrials.gov/study/NCT04348747]