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Vaccine Detail

c-di-GMP [c- diguanylate]
Vaccine Information
  • Vaccine Name: c-di-GMP [c- diguanylate]
  • Target Pathogen: Klebsiella pneumoniae
  • Target Disease: Pneumonia, Bloodstream infections, Abscess
  • Type: Subunit vaccine
  • Status: Research
  • Host Species for Licensed Use: Mouse
  • Antigen: The c-di-GMP used in these studies was chemically synthesized and prepared (Karaolis et al., 2007)
  • Preparation: The c-di-GMP used in these studies was chemically synthesized and prepared (Karaolis et al., 2007)
  • Immunization Route: i.t.
Host Response
References
Karaolis et al., 2007: Karaolis DK, Newstead MW, Zeng X, Hyodo M, Hayakawa Y, Bhan U, Liang H, Standiford TJ. Cyclic di-GMP stimulates protective innate immunity in bacterial pneumonia. Infection and immunity. 2007; 75(10); 4942-4950. [PubMed: 17646358].