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Vaccine Detail
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CpG ODN (Two CpG motifs) |
| Vaccine Information |
- Vaccine Name: CpG ODN (Two CpG motifs)
- Target Pathogen: Klebsiella pneumoniae
- Target Disease: Pneumonia, Bloodstream infections, Abscess
- Type: Subunit vaccine
- Status: Research
- Host Species for Licensed Use: Mouse
- Antigen: Synthetic oligodeoxynucleotides (ODN) containing unmethylated CpG dinucleotide motifs (CpG ODN) (Deng et al., 2004)
- Preparation: Active and control CpG ODN were synthesized on a phosphodiester backbone by Oligos Etc. (Deng et al., 2004)
- Immunization Route: i.t.
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| Host Response |
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| References |
Deng et al., 2004: Deng JC, Moore TA, Newstead MW, Zeng X, Krieg AM, Standiford TJ. CpG oligodeoxynucleotides stimulate protective innate immunity against pulmonary Klebsiella infection. Journal of immunology (Baltimore, Md. : 1950). 2004; 173(8); 5148-5155. [PubMed: 15470059].
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