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Vaccine Detail
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CRM197-1 (Synthetic hexasaccharide) |
| Vaccine Information |
- Vaccine Name: CRM197-1 (Synthetic hexasaccharide)
- Target Pathogen: Klebsiella pneumoniae
- Target Disease: Pneumonia, Bloodstream infections, Abscess
- Type: Conjugate vaccine
- Status: Research
- Host Species for Licensed Use: Mouse
- Antigen: CRM197-1 (Synthetic hexasaccharide) (Seeberger et al., 2017)
- Preparation: the convergent [3+3] synthesis of the hexasaccharide repeating unit from its capsular polysaccharide and related sequences (Seeberger et al., 2017)
- Immunization Route: subcutaneous injection
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| Host Response |
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| References |
Seeberger et al., 2017: Seeberger PH, Pereira CL, Khan N, Xiao G, Diago-Navarro E, Reppe K, Opitz B, Fries BC, Witzenrath M. A Semi-Synthetic Glycoconjugate Vaccine Candidate for Carbapenem-Resistant Klebsiella pneumoniae. Angewandte Chemie (International ed. in English). 2017; 56(45); 13973-13978. [PubMed: 28815890].
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