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Vaccine Detail

ChAd155-RG
Vaccine Information
  • Vaccine Name: ChAd155-RG
  • Target Pathogen: Rabies virus
  • Target Disease: Rabies
  • Type: Recombinant vector vaccine
  • Status: Clinical trial
  • Host Species for Licensed Use: Human
  • Antigen: RG vaccine antigen, RGN antigen, RNG vaccine antigens were inserted and evaluated in the CAd155 vector. (Napolitano et al., 2020)
  • Preparation: One dose (1 ml (5x10^10 vp)) of ChAd155-RG vaccine administered intramuscularly on Day 1, and 1 ml of matching placebo administered intramuscularly on Days 8, 15, 22. N=14 (3 sentinel, 11 non-sentinel) (Napolitano et al., 2020)
  • Immunization Route: Intramuscular injection (i.m.)
  • Description: The ChAd155-RG Vaccine consists of a replication-defective group C ChAd, ChAd155, expressing RG under the control of the CMV promoter. The RG sequence cloned into the ChAd155 vector is a medoid, a natural viral strain. (Napolitano et al., 2020)
Host Response
References