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Vaccine Detail

ChAdOx2 RabG
Vaccine Information
  • Vaccine Name: ChAdOx2 RabG
  • Target Pathogen: Rabies virus
  • Target Disease: Rabies
  • Type: Inactivated or "killed" vaccine
  • Status: Licensed
  • Host Species for Licensed Use: Human
  • Antigen: Full length glycoprotein (Wang et al., 2018)
  • Preparation: In two independent preparations results were:
    1)Yield of 5.0x1012 VP / 9.0x1010 IU (P:I ratio = 54) from 5x107 cells
    2)Yield of 1.9x1013 VP / 2.1x1011 IU (P:I ratio = 92) from 1.5x108 cells(Wang et al., 2018)
  • Immunization Route: Intramuscular injection (i.m.)
  • Storage: stored at -80 °C
  • Description: ChAdOx2 RabG uses the chimpanzee adenovirus serotype 68 and is based upon a simian adenovirus-vectored candidate previously shown to achieve protection after a single dose in non-human primates. (Wang et al., 2018)
Host Response
References