- Vaccine Name: ACAM3000
- Target Pathogen: Variola virus
- Target Disease: Smallpox
- Product Name: Smallpox (Vaccinia) Vaccine, Live
- Manufacturer: ACAMBIS, Inc
- Type: Replication competent virus
- Status: Licensed
- Location Licensed: Cambridge, MA
- Host Species for Licensed Use: Human
- Preparation: ACAM3000 was formulated with 20mM Tris, 0.9% NaCl USP, and 0.01% neomycin USP with a titer of 2.54 × 108 TCID50/mL. The vaccine was reconstituted with 0.9% NaCl and diluted to the appropriate dose. Sterile saline, 0.9% NaCl, was used as the placebo. The dose of MVA administered was verified by back titration for each dose tier that was studied.(Wilck et al., 2010)
- Immunization Route: Intramuscular injection (i.m.)
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