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Vaccine Detail
WNV recombinant E protein vaccine (WN-80E) |
Vaccine Information |
- Vaccine Name: WNV recombinant E protein vaccine (WN-80E)
- Target Pathogen: West Nile virus
- Target Disease: West Nile fever
- Manufacturer: Hawaii Biotech
- Type: Recombinant E subunit vaccine
- Status: Licensed
- Host Species for Licensed Use: Human
- Antigen: WNV E protein antigen (Van et al., 2016).
- Immunization Route: Intramuscular injection (i.m.)
- Storage: Virus was aliquoted and stored at -80C.
- Description: WNV recombinant E-protein vaccine (WN-80E) is combined with a synthetic TLR-4 agonist adjuvant. inclusion of a TLR-4 agonist in either a stable oil-in-water emulsion (SE) or aluminum hydroxide (Alum) formulation provides both dose and dosage sparing functions, whereby protection can be induced after a single immunization containing only 100 ng of WN-80E.(Van et al., 2016)
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Host Response |
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