• Vaccine Name: XRX-001
• Target Pathogen: Yellow fever virus
• Target Disease: Yellow fever
• Type: Inactivated or "killed" vaccine
• Status: Licensed
• Host Species for Licensed Use: Human
• Immunization Route: Intramuscular injection (i.m.)
• Description: XRX-001 is an inactivated vaccine candidate based on a β-propriolactone-inactivated virus generated in cell culture. Multiple dose administration is required when administered.(Montalvo et al., 2022)

Hamster Response

• Immune Response: This vaccine candidate conferred protection to hamsters against lethal challenge through passive immunization and resulted in the generation of neutralizing antibody titers in cynomolgus macaques.(Montalvo et al., 2022)