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Vaccine Detail

T. cruzi DNA vaccine encoding TSSA
Vaccine Information
  • Vaccine Name: T. cruzi DNA vaccine encoding TSSA
  • Target Pathogen: Trypanosoma cruzi
  • Target Disease: Chagas disease
  • Type: DNA vaccine
  • Status: Research
  • Host Species for Licensed Use: Mouse
  • Antigen: TSSA (Katae et al., 2002)
  • Immunization Route: Intramuscular injection (i.m.)
  • Description: T. cruzi DNA vaccine encoding TSSA antigen enhanced by IL-12 adjuvant
Host Response
References
Katae et al., 2002: Katae M, Miyahira Y, Takeda K, Matsuda H, Yagita H, Okumura K, Takeuchi T, Kamiyama T, Ohwada A, Fukuchi Y, Aoki T. Coadministration of an interleukin-12 gene and a Trypanosoma cruzi gene improves vaccine efficacy. Infection and immunity. 2002; 70(9); 4833-4840. [PubMed: 12183527].