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Vaccine Detail
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Mnull RSV |
| Vaccine Information |
- Vaccine Name: Mnull RSV
- Target Pathogen: Human Respiratory Syncytial Virus
- Target Disease: Respiratory tract disease
- Type: Live, attenuated vaccine
- Status: Clinical trial
- Host Species for Licensed Use: None
- Host Species as Laboratory Animal Model: Baboons
- Antigen: Fusion (F) protein
- M protein
gene engineering:
- Type: Recombinant protein preparation
- Description: Deletion of RSV M protein. (Ivanov et al., 2021)
- Detailed Gene Information: Click Here.
- Preparation: RSV M protein was deleted (Ivanov et al., 2021).
- Immunization Route: intranasal immunization
- Description: Mnull RSV is derived from a human RSV A2 strain. The gene for the RSV M protein has been deleted. Mnull RSV is grown in HEp-2 respiratory epithelial cells transfected to express the viral M protein. The vaccine virus is fully infectious, and synthesizes all of its proteins (except M) after entering HEp-2 cells (Ivanov et al., 2021).
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| References |
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