• Vaccine Name: Influenza vaccine with adjuvant 1V270
• Target Pathogen: Influenza virus
• Target Disease: Influenza (flu)
• Type: Inactivated or "killed" vaccine
• Status: Research
• Host Species for Licensed Use: Mouse
• Adjuvant:
  • Adjuvant name:
  • VO adjuvant ID: VO_0005270
• Preparation: A prime-boost vaccination protocol of IIAV adjuvanted with 2B182C --> the co-encapsulation of 1V270 and 2B182C in a liposome
• Immunization Route: Intramuscular injection (i.m.)

Mouse Response

• Immune Response: induced anti-HA and anti-NA IgG1 production and enhanced antigen specific IgG2a production induced by the TLR7 agonist 1V270; Th1 and Th2 associated antibody responses against IIAV + enhanced clonal expansion of B cells in the GC