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Vaccine Detail

SARS-CoV S Baculovirus Vaccine
Vaccine Information
  • Vaccine Name: SARS-CoV S Baculovirus Vaccine
  • Target Pathogen: SARS-CoV
  • Target Disease: Severe Acute Respiratory Syndrome (SARS)
  • Type: Recombinant vector vaccine
  • Status: Research
  • Host Species for Licensed Use: None
  • Host Species as Laboratory Animal Model: Mouse, Rat
  • Antigen: S protein of SARS-CoV (Zhou et al., 2006)
  • Immunization Route: intranasal immunization
  • Description: recombinant SARS-CoV spike (S) glycoprotein viral vaccine produced in insect cells that is expressed by baculovirus (Zhou et al., 2006)
Host Response
References
Zhou et al., 2006: Zhou Z, Post P, Chubet R, Holtz K, McPherson C, Petric M, Cox M. A recombinant baculovirus-expressed S glycoprotein vaccine elicits high titers of SARS-associated coronavirus (SARS-CoV) neutralizing antibodies in mice. Vaccine. 2006; 24(17); 3624-3631. [PubMed: 16497416].