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Vaccine Detail
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H. pylori AhpC vaccine |
| Vaccine Information |
- Vaccine Name: H. pylori AhpC vaccine
- Target Pathogen: Helicobacter pylori
- Target Disease: Ulcers
- Type: Recombinant vector vaccine
- Status: Research
- Host Species for Licensed Use: Baboon
- Host Species as Laboratory Animal Model: Mice
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Adjuvant:
50% of mice immunized systemically with AhpC adjuvanted with alum (AhpC/alum) were shown to be protected from infection with H. pylori whereas 30% protection was observed for mice immunized systemically with AhpC alone (O'Riordan et al., 2012).
- Immunization Route: subcutaneous injection
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| Host Response |
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| References |
O'Riordan et al., 2012: O'Riordan AA, Morales VA, Mulligan L, Faheem N, Windle HJ, Kelleher DP. Alkyl hydroperoxide reductase: a candidate Helicobacter pylori vaccine. Vaccine. 2012; 30(26); 3876-3884. [PubMed: 22512976].
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