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Vaccine Detail

Vaxchora
Vaccine Information
  • Vaccine Name: Vaxchora
  • Target Pathogen: Vibrio cholerae
  • Target Disease: Cholera
  • Tradename: Vaxchora
  • Manufacturer: PaxVax, Inc.
  • CDC CVX code: 174
  • Type: Live, attenuated vaccine
  • Status: Licensed
  • Location Licensed: USA
  • Host Species for Licensed Use: Human
  • Immunization Route: Oral
  • Storage: Store at −25°C to −15°C (−13°F to 5°F), and protect from light and moisture.
  • Approved Age for Licensed Use: 18 to 64 years of age.
  • Description: VAXCHORA (Cholera Vaccine, Live, Oral) is a live, attenuated bacterial vaccine suspension for oral administration containing the V. cholerae strain CVD 103-HgR. CVD 103-HgR was constructed from the serogroup O1 classical Inaba strain 569B by deleting the catalytic domain sequence of both copies of the ctxA gene, which prevents the synthesis of active cholera toxin (CT). (FDA: Vaxchora)
Host Response
References
FDA: Vaxchora: FDA: Vaxchora vaccine information [https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM506235.pdf]