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Vaccine Detail

Adenovirus 5-Fibroblast Growth Factor 2
Vaccine Information
  • Vaccine Name: Adenovirus 5-Fibroblast Growth Factor 2
  • Target Pathogen: Cancer
  • Target Disease: Cancer
  • Vaccine Ontology ID: VO_0007201
  • Type: Other
  • Status: Research
  • Host Species for Licensed Use: Human
  • Host Species as Laboratory Animal Model: Human
  • FGF2 gene engineering:
    • Type: Recombinant protein preparation
    • Description:
    • Detailed Gene Information: Click Here.
  • Description: Fibroblast growth factor-2-retargeted adenoviral vectors may be used to increase the transduction of GBM-derived endothelial cells, enabling a new and efficient anti-angiogenesis strategy for the treatment of malignant gliomas.(Gupta et al., 2006)
Host Response
References
Gupta et al., 2006: Gupta V, Wang W, Sosnowski BA, Hofman FM, Chen TC. Fibroblast growth factor-2-retargeted adenoviral vector for selective transduction of primary glioblastoma multiforme endothelial cells. Neurosurgical focus. 2006; 20(4); E26. [PubMed: 16709032].