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Vaccine Detail
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Personalized Synthetic Long Peptide Breast Cancer Vaccine |
| Vaccine Information |
- Vaccine Name: Personalized Synthetic Long Peptide Breast Cancer Vaccine
- Target Pathogen: Cancer
- Target Disease: Cancer
- Vaccine Ontology ID: VO_0007010
- Type: Recombinant vector vaccine
- Status: Clinical trial
- Host Species for Licensed Use: Human
- Host Species as Laboratory Animal Model: Human
- Description: This is for Breast Cancer (NCT02427581).A cancer vaccine consisting of one or more long, synthetic peptides derived from patient-specific breast cancer tumor-associated antigens (TAAs), with potential immunomodulating and antineoplastic activities. Upon intramuscular administration of the personalized synthetic long peptide breast cancer vaccine, the peptides stimulate the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing the TAAs, which results in tumor cell lysis. (NCIT_C121947).
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| Host Response |
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| References |
NCIT_C121947: [https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C121947]
NCT02427581: [https://clinicaltrials.gov/ct2/show/NCT02427581]
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