VIOLIN: Vaccine Investigation and Online Information Network

Vaccine Detail

5CVMB

Vaccine Information

Vaccine Name: 5CVMB
Target Pathogen: Neisseria meningitidis
Target Disease: Meningitis
Vaccine Ontology ID: VO_0011348
Type: Subunit vaccine
Status: Licensed
Antigen: Five antigens are included: GNA2132, GNA1870, NadA, GNA1030, and GNA2091 (Giuliani et al., 2006)
Adjuvant: aluminum hydroxide vaccine adjuvant
- Adjuvant name: aluminum hydroxide vaccine adjuvant
- VO adjuvant ID: VO_0000127
- Description: Adjuvant: aluminum hydroxide combined with CpG oligonucleotides (Giuliani et al., 2006)
Adjuvant: CpG DNA vaccine adjuvant
- Adjuvant name: CpG DNA vaccine adjuvant
- VO adjuvant ID: VO_0001237
- Description: aluminum hydroxide combined with CpG oligonucleotides (Giuliani et al., 2006).
Immunization Route: Intraperitoneal injection (i.p.)

Host Response

References

Giuliani et al., 2006: Giuliani MM, Adu-Bobie J, Comanducci M, Aricò B, Savino S, Santini L, Brunelli B, Bambini S, Biolchi A, Capecchi B, Cartocci E, Ciucchi L, Di Marcello F, Ferlicca F, Galli B, Luzzi E, Masignani V, Serruto D, Veggi D, Contorni M, Morandi M, Bartalesi A, Cinotti V, Mannucci D, Titta F, Ovidi E, Welsch JA, Granoff D, Rappuoli R, Pizza M. A universal vaccine for serogroup B meningococcus. Proceedings of the National Academy of Sciences of the United States of America. 2006; 103(29); 10834-10839. [PubMed: 16825336].