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Vaccine Detail
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2008–2009 trivalent influenza vaccine |
| Vaccine Information |
- Vaccine Name: 2008–2009 trivalent influenza vaccine
- Target Pathogen: Influenza virus
- Target Disease: Influenza (flu)
- Tradename: A/Brisbane/59/2007(H1N1), A/Brisbane/10/2007(H3N2), B/Florida/4/2006; Sanofi-Pasteur
- Vaccine Ontology ID: VO_0004809
- Type: Inactivated or "killed" vaccine
- Status: Licensed
- Host Species for Licensed Use: Human
- Immunization Route: Intramuscular injection (i.m.)
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| Host Response |
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Human Response
- Vaccination Protocol: Participants were immunized on day 0 with the 2008–2009 trivalent influenza vaccine. (Bucasas et al., 2011)
- Immune Response: Identified expression changes in 4740 transcripts. (Bucasas et al., 2011)
- Host ADA response
- Description: 2008–2009 trivalent influenza vaccine induced upregulation of ADA in PBMC's on day 1 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host ASH1L response
- Description: 2008–2009 trivalent influenza vaccine induced upregulation of ASHL1 in PBMC's on day 1 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host CASP1 response
- Description: 2008-2009 trivalent vaccine induced upregulation of CASP1 in PBMC's on day 1 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host CCND3 response
- Description: 2008-2009 trivalent vaccine induced upregulation of CCND3 in PBMC's on day 1 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host CYLD response
- Description: 2008–2009 trivalent influenza vaccine induced upregulation of CYLD in PBMC's on day 1 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host DDX21 response
- Description: 2008-2009 trivalent vaccine induced upregulation of DDX21 in PBMC's on day 1 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host DDX41 response
- Description: 2008-2009 trivalent vaccine induced upregulation of DDX41 in PBMC's on day 1 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host E2F2 response
- Description: 2008-2009 trivalent vaccine induced downregulation of E2F2 in PBMC's on day 3 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host E2F2 response
- Description: 2008-2009 trivalent vaccine induced upregulation of E2F2 in PBMC's on day 1 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host E2F2 response
- Description: 2008-2009 trivalent vaccine induced upregulation of E2F2 in PBMC's on day 1 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host ERCC1 response
- Description: 2008-2009 trivalent vaccine induced upregulation of ERCC1 in PBMC's on day 1 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host EXOSC3 response
- Description: 2008-2009 trivalent vaccine induced upregulation of EXOSC3 in PBMC's on day 1 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host EXOSC3 response
- Description: 2008-2009 trivalent vaccine induced upregulation of EXOSC3 in PBMC's on day 1 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host FCER1G response
- Description: 2008–2009 trivalent influenza vaccine induced upregulation of FCER1G in PBMC's on day 1 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host HNRNPU response
- Description: 2008-2009 trivalent vaccine induced upregulation of HNRNPU in PBMC's on day 1 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host IL2 response
- Description: 2008–2009 trivalent influenza vaccine induced upregulation of IL2 in PBMC's on day 1 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host IL6 response
- Description: 2008-2009 trivalent vaccine induced upregulation of IL-6 in PBMC's on day 1 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host JAK2 response
- Description: 2008-2009 trivalent vaccine induced upregulation of JAK2 in PBMC's on day 1 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host LYN response
- Description: 2008-2009 trivalent vaccine induced upregulation of LYN in PBMC's on day 1 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host MYD88 response
- Description: 2008–2009 trivalent influenza vaccine induced upregulation of MYD88 in PBMC's on day 1 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host NFKBIA response
- Description: 2008-2009 trivalent vaccine induced upregulation of NFKBIA in PBMC's on day 1 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host OASL response
- Description: 2008-2009 trivalent vaccine induced upregulation of OASL in PBMC's on day 1 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host POLR3E response
- Description: 2008-2009 trivalent vaccine induced upregulation of POLR3E in PBMC's on day 1 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host PQBP1 response
- Description: 2008–2009 trivalent influenza vaccine induced upregulation of PQBP1 in PBMC's on day 14 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host RIPK2 response
- Description: 2008–2009 trivalent influenza vaccine induced upregulation of RIPK2 in PBMC's on day 1 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host S100A4 response
- Description: 2008–2009 trivalent influenza vaccine induced upregulation of S100A4 in PBMC's on day 1 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host SLFN11 response
- Description: 2008-2009 trivalent vaccine induced upregulation of SLFN11 in PBMC's on day 1 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host STAT1 response
- Description: 2008-2009 trivalent vaccine induced upregulation of STAT1 in PBMC's on day 1 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host STAT4 response
- Description: 2008-2009 trivalent vaccine induced upregulation of STAT4 in PBMC's on day 1 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host TLR7 response
- Description: 2008–2009 trivalent influenza vaccine induced upregulation of TLR7 in PBMC's on day 1(Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host TLR8 response
- Description: 2008–2009 trivalent influenza vaccine induced upregulation of TLR8 in PBMC's on day 1 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host TRAF3IP3 response
- Description: 2008-2009 trivalent vaccine induced upregulation of TRAF3IP3 in PBMC's on day 1 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host USP14 response
- Description: 2008–2009 trivalent influenza vaccine induced upregulation of USP14 in PBMC's on day 1 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host ZNF112 response
- Description: 2008–2009 trivalent influenza vaccine induced upregulation of ZNF112 in PBMC's on day 14 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
- Host ZNF224 response
- Description: 2008–2009 trivalent influenza vaccine induced upregulation of ZNF224 in PBMC's on day 14 (Bucasas et al., 2011).
- Detailed Gene Information: Click Here.
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| References |
Bucasas et al., 2011: Bucasas KL, Franco LM, Shaw CA, Bray MS, Wells JM, Niño D, Arden N, Quarles JM, Couch RB, Belmont JW. Early patterns of gene expression correlate with the humoral immune response to influenza vaccination in humans. The Journal of infectious diseases. 2011; 203(7); 921-929. [PubMed: 21357945].
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