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Vaccine Detail
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rVEE-Ebola-NP |
| Vaccine Information |
- Vaccine Name: rVEE-Ebola-NP
- Target Pathogen: Ebola virus
- Target Disease: Ebola hemorrhagic fever
- Vaccine Ontology ID: VO_0004805
- Type: Recombinant vector vaccine
- Status: Research
- Host Species for Licensed Use: Baboon
- Antigen: Ebola virus nucleoprotein (NP) (Wilson and Hart, 2001)
- NP from Zaire Ebola virus
gene engineering:
- Type: Recombinant vector construction
- Description:
- Detailed Gene Information: Click Here.
- Vector:
- Immunization Route: Intramuscular injection (i.m.)
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| Host Response |
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Mouse Response
- Host Strain: C57BL/6
- Vaccine Immune Response Type: VO_0003057
- Efficacy: C57BL/6 mice vaccinated with Venezuelan equine encephalitis virus replicons encoding the Ebola virus nucleoprotein (NP) survived lethal challenge with Ebola virus (Wilson and Hart, 2001).
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| References |
Wilson and Hart, 2001: Wilson JA, Hart MK. Protection from Ebola virus mediated by cytotoxic T lymphocytes specific for the viral nucleoprotein. Journal of virology. 2001; 75(6); 2660-2664. [PubMed: 11222689].
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