• Vaccine Name: rCPV-BTV-Cpox
• Target Pathogen: Bluetongue virus
• Target Disease: Bluetongue disesase
• Vaccine Ontology ID: VO_0004788
• Type: Recombinant vector vaccine
• Status: Research
• Host Species for Licensed Use: Baboon
• Vector:
  • Vector name:
  • VO vector ID: VO_0001115
  • Description: (Perrin et al., 2007)
• Preparation: BTV recombinant capripoxviruses (BTV-Cpox) individually expressing four different genes encoding two capsid proteins (VP2 and VP7) and two non-structural proteins (NS1, NS3) of BTV serotype 2 (BTV-2) (Perrin et al., 2007).
• Immunization Route: Intramuscular injection (i.m.)

Sheep Response

• Vaccination Protocol: Sheep were immunized with BTV recombinant capripoxviruses (BTV-Cpox) (Perrin et al., 2007).
• Vaccine Immune Response Type: VO_0000287
• Challenge Protocol: The sheep were challenged with a virulent strain of BTV-2 (Perrin et al., 2007).
• Efficacy: Sheep challenged 3 weeks after BTV-Cpox vaccination exhibited partial protection (Perrin et al., 2007).