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Vaccine Detail

MG1-hDCT Vaccine
Vaccine Information
  • Vaccine Name: MG1-hDCT Vaccine
  • Target Pathogen: Cancer
  • Target Disease: Cancer
  • Vaccine Ontology ID: VO_0004764
  • Type: Recombinant vector vaccine
  • Status: Research
  • Host Species for Licensed Use: Baboon
  • MAGE-1 gene engineering:
    • Type: Recombinant protein preparation
    • Description: (Sang et al., 2011)
    • Detailed Gene Information: Click Here.
  • Vector:
  • Preparation: (Pol et al., 2014) an attenuated Maraba strain, defined as MG1, to express a melanoma-associated tumor antigen.
  • Immunization Route: Intramuscular injection (i.m.)
Host Response
References
Pol et al., 2014: Pol JG, Zhang L, Bridle BW, Stephenson KB, Ress├ęguier J, Hanson S, Chen L, Kazdhan N, Bramson JL, Stojdl DF, Wan Y, Lichty BD. Maraba virus as a potent oncolytic vaccine vector. Molecular therapy : the journal of the American Society of Gene Therapy. 2014; 22(2); 420-429. [PubMed: 24322333].
Sang et al., 2011: Sang M, Wang L, Ding C, Zhou X, Wang B, Wang L, Lian Y, Shan B. Melanoma-associated antigen genes - an update. Cancer letters. 2011; 302(2); 85-90. [PubMed: 21093980].