• Vaccine Name: rLSDV-RPV
• Target Pathogen: rinderpest virus
• Vaccine Ontology ID: VO_0004763
• Type: Recombinant vector vaccine
• Status: Research
• Host Species for Licensed Use: Baboon
• Vector:
  • Vector name:
  • VO vector ID: VO_0001111
• Preparation: Recombinant capripox-rinderpest vaccine (Ngichabe et al., 2002).
• Immunization Route: Intramuscular injection (i.m.)

Cattle Response

• Vaccination Protocol: A dose of 10^5.3 TCID50/ml of the recombinant vaccine, determined previously as an effective dose, was injected subcutaneously in the shoulder region of each animal (Ngichabe et al., 2002).
• Vaccine Immune Response Type: VO_0003057
• Challenge Protocol: Two years after vaccination, cattle were challenged with virulent RPV (Ngichabe et al., 2002).
• Efficacy: In the case of LSDV, all of 4 vaccinated cattle challenged with virulent LSDV at 2 years were completely protected from clinical disease while 2 of 5 vaccinated cattle were completely protected at 3 years. The recombinant vaccine showed no loss of potency when stored lyophylized at 4 degrees C for up to 1 year (Ngichabe et al., 2002).