• Vaccine Name: rMVA- AHS-VP2
• Target Pathogen: African horse sickness virus
• Vaccine Ontology ID: VO_0004758
• Type: Recombinant vector vaccine
• Status: Research
• Host Species for Licensed Use: Baboon
• Vector:
  • Vector name:
  • VO vector ID: VO_0001107
  • Description: (Castillo-Olivares et al., 2011)
• Preparation: Recombinant vaccine based on modified vaccinia Ankara expressing AHS-4 VP2 (MVA-VP2) (Castillo-Olivares et al., 2011).
• Immunization Route: Intramuscular injection (i.m.)

Mouse Response

• Vaccination Protocol: The mice were vaccinated by the intra-peritoneal route on days 0 and 28 with 10^7 pfu of MVA-VP2 per mouse (Castillo-Olivares et al., 2011).
• Vaccine Immune Response Type: VO_0000287
• Challenge Protocol: The mice were subsequently challenged on day 35 with 106 pfu of AHSV-4 (Castillo-Olivares et al., 2011).
• Efficacy: All of the MVA-VP2 vaccinated animals were also protected from clinical signs and were completely healthy until the end of the study period (Castillo-Olivares et al., 2011).