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Vaccine Detail

BV-GD-ORF2
Vaccine Information
  • Vaccine Name: BV-GD-ORF2
  • Target Pathogen: Porcine circovirus 2
  • Target Disease: Postweaning multisystemic wasting syndrome
  • Vaccine Ontology ID: VO_0004754
  • Type: Recombinant vector vaccine
  • Status: Research
  • Host Species for Licensed Use: Baboon
  • Vector:
  • Preparation: B aculovirus was used to develop a novel candidate vaccine for a preventive or therapeutic strategy to control PCV2 infections (Ye et al., 2013).
  • Immunization Route: Intramuscular injection (i.m.)
Host Response

Mouse Response

  • Vaccination Protocol: BALB/c mice were immunized intramuscularly with this baculovirus (Ye et al., 2013).
  • Vaccine Immune Response Type: VO_0003057
  • Efficacy: The vaccination of mice with recombinant baculovirus BV-GD-ORF2 successfully induced robust Cap-protein-specific humoral and cellular immune responses (Ye et al., 2013).
References
Ye et al., 2013: Ye Y, Cheng X, Zhang J, Tong T, Lin W, Liao M, Fan H. Induction of robust immunity response in mice by dual-expression-system-based recombinant baculovirus expressing the capsid protein of porcine circovirus type 2. Virology journal. 2013; 10; 316. [PubMed: 24161107].