• Vaccine Name: rFP-RPV-H/F
• Target Pathogen: rinderpest virus
• Vaccine Ontology ID: VO_0004752
• Type: Recombinant vector vaccine
• Status: Research
• Host Species for Licensed Use: Baboon
• Vector:
  • Vector name:
  • VO vector ID: VO_0001040
• Preparation: Rinderpest virus (RPV) antigens, expressed in pox virus vectors (Jones et al., 1997).
• Immunization Route: Intramuscular injection (i.m.)

Ferret Response

• Vaccination Protocol: Ferrets were inoculated intradermally with recombinant vaccinia viruses expressing the H gene of RPV, the F gene of RPV, the H and F genes of RPV, or fowlpox virus recombinant expressing both genes. Two ferrets were vaccinated s.c. with CDV vaccine as positive controls, and 1 group was left unvaccinated as a negative control (Jones et al., 1997).
• Vaccine Immune Response Type: VO_0003057
• Challenge Protocol: The ferrets were challenge exposed with a high dose of CDV (Jones et al., 1997).
• Efficacy: Partial protection was seen in all groups, with vRVFH vaccination being the most protective (Jones et al., 1997).