• Vaccine Name: rMDV-IBDV-VP2
• Target Pathogen: Infectious Bursal Disease Virus (IBDV)
• Target Disease: Infectious Bursal Disease
• Vaccine Ontology ID: VO_0004749
• Type: Recombinant vector vaccine
• Status: Research
• Host Species for Licensed Use: Baboon
• VP2 gene engineering:
  • Type: Recombinant vector construction
  • Description: IBDV host-protective antigen VP2 was expressed in a recombinant vaccine vector (Tsukamoto et al., 2000).
  • Detailed Gene Information: Click Here.
• Vector: herpesvirus of turkey vaccine vector
  • Vector name: herpesvirus of turkey vaccine vector
  • VO vector ID: VO_0001067
• Preparation: Marek's disease and Fowlpox viruses expressing the vvIBDV host-protective antigen VP2 (rMDV, rFPV) (Tsukamoto et al., 2000).
• Immunization Route: Intramuscular injection (i.m.)

Chicken Response

• Vaccination Protocol: Chickens vaccinated with the rFPV or rMDV alone, or vaccinated simultaneously with both at their hatch (rMDV-rFPV(1d)) (Tsukamoto et al., 2000).
• Vaccine Immune Response Type: VO_0003057
• Efficacy: Most chickens were protected against developing clinical signs and mortality; however, only zero to 14% of the chickens were protected against gross lesions (Tsukamoto et al., 2000).