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Vaccine Detail
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rNDV-H6 |
| Vaccine Information |
- Vaccine Name: rNDV-H6
- Target Pathogen: Influenza virus
- Target Disease: Influenza (flu)
- Vaccine Ontology ID: VO_0004683
- Type: Recombinant vector vaccine
- Status: Research
- Host Species for Licensed Use: Chicken
- Vector:
- Preparation: A recombinant Newcastle disease virus (NDV) expressing H6 hemagglutinin (HA) of a low pathogenic avian influenza virus (LPAIV) was generated by reverse genetics (NDVH6) (Schröer et al., 2011).
- Immunization Route: Intramuscular injection (i.m.)
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| Host Response |
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Chicken Response
- Vaccine Immune Response Type: VO_0003057
- Efficacy: A single vaccination protected specific-pathogen-free (SPF) chickens against a subsequent lethal NDV infection and prevented shedding of AIV after homologous H6 LPAIV infection (Schröer et al., 2011).
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| References |
Schröer et al., 2011: Schröer D, Veits J, Keil G, Römer-Oberdörfer A, Weber S, Mettenleiter TC. Efficacy of Newcastle disease virus recombinant expressing avian influenza virus H6 hemagglutinin against Newcastle disease and low pathogenic avian influenza in chickens and turkeys. Avian diseases. 2011; 55(2); 201-211. [PubMed: 21793434].
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