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Vaccine Detail
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rNDV-H5 ( HPAI H5N1 challenge in mule ducks) |
| Vaccine Information |
- Vaccine Name: rNDV-H5 ( HPAI H5N1 challenge in mule ducks)
- Target Pathogen: Influenza virus
- Target Disease: Influenza (flu)
- Vaccine Ontology ID: VO_0004682
- Type: Recombinant vector vaccine
- Status: Research
- Host Species for Licensed Use: Baboon
- Vector:
- Preparation: Newcastle disease virus (NDV) vector expressing an H5N1 hemagglutinin (rNDV-H5) (Ferreira et al., 2012).
- Immunization Route: Intramuscular injection (i.m.)
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| Host Response |
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Ducks Response
- Vaccination Protocol: The ducks were vaccinated with NDV-H5 (Ferreira et al., 2012).
- Vaccine Immune Response Type: VO_0003057
- Efficacy: Our results showed the rNDV-H5 vaccine elicits satisfactory humoral and cellular responses in 11-day-old ducks correlating with a complete clinical and virological protection against the H5N1 strain (Ferreira et al., 2012).
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| References |
Ferreira et al., 2012: Ferreira HL, Pirlot JF, Reynard F, van den Berg T, Bublot M, Lambrecht B. Immune responses and protection against H5N1 highly pathogenic avian influenza virus induced by the Newcastle disease virus H5 vaccine in ducks. Avian diseases. 2012; 56(4 Suppl); 940-948. [PubMed: 23402116].
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