• Vaccine Name: Listeria-LJM11
• Target Pathogen: cutaneous leishmaniasis
• Type: Recombinant vector vaccine
• Status: Research
• Host Species for Licensed Use: Baboon
• Vector:
  • Vector name:
  • VO vector ID: VO_0000068
  • Description: (Abi et al., 2014)
• Preparation: Attenuated strain of Listeria monocytogenes as a vaccine expression system for LJM11 (Abi et al., 2014).
• Immunization Route: Intramuscular injection (i.m.)

Mouse Response

• Vaccination Protocol: Mice were vaccinated intravenously with LJM11 (Abi et al., 2014).
• Vaccine Immune Response Type: VO_0003057
• Challenge Protocol: Mice were intradermally challenged with Leishmania major and sand fly saliva (Abi et al., 2014).
• Efficacy: Mice were best protected when vaccinated intravenously. However, this protection was short-lived. Importantly, groups of vaccinated mice were protected long term when challenged with infected sand flies (Abi et al., 2014).