• Vaccine Name: rSPV-PCV2-cap
• Target Pathogen: Porcine circovirus 2
• Target Disease: Postweaning multisystemic wasting syndrome
• Product Name: recombinant swinepox virus expressing PCV2 capsid protein
• Vaccine Ontology ID: VO_0004619
• Type: Recombinant vector vaccine
• Status: Research
• Host Species for Licensed Use: Baboon
• Antigen: PCV2 capsid
• Preparation: Recombinant swinepox virus expressing capsid protein (rSPV-cap) (Lin et al., 2012).
• Immunization Route: Intramuscular injection (i.m.)

Pig Response

• Vaccination Protocol: Pigs were immunized with rSPV-cap, wild type SPV (wtSPV; negative control), or PBS (challenge control) (Lin et al., 2012).
• Vaccine Immune Response Type: VO_0003057
• Challenge Protocol: Vaccinated pigs were challenged with PCV2 (Lin et al., 2012).
• Efficacy: After inoculation with PCV2, pigs in the rSPV-cap immunized group showed significantly higher average daily weight gain (ADG) and shorter fever duration compared with the wtSPV treated group. The results suggested that the recombinant rSPV-cap provided pigs with significant protection from PCV2-associated disease (Lin et al., 2012).