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Vaccine Detail
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short overlapping peptides and full-length recombinant protein |
| Vaccine Information |
- Vaccine Name: short overlapping peptides and full-length recombinant protein
- Target Pathogen: Cancer
- Target Disease: Cancer
- Vaccine Ontology ID: VO_0004617
- Type: peptide
- Status: Licensed
- Antigen: NY-ESO-1
- CTAG1B
gene engineering:
- Immunization Route: Intramuscular injection (i.m.)
- Description: In this study, we finely mapped linear antibody epitopes using sera from melanoma patients and shorter overlapping peptide sets. We have shown that melanoma patients' humoral immune systems responded to NY-ESO-1 differently in each individual with widely differing antibody specificity, intensity and antibody subtypes (Komatsu et al., 2013).
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| Host Response |
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| References |
Komatsu et al., 2013: Komatsu N, Jackson HM, Chan KF, Oveissi S, Cebon J, Itoh K, Chen W. Fine-mapping naturally occurring NY-ESO-1 antibody epitopes in melanoma patients' sera using short overlapping peptides and full-length recombinant protein. Molecular immunology. 2013; 54(3-4); 465-471. [PubMed: 23454162].
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