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Vaccine Detail
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IL-12p70 |
| Vaccine Information |
- Vaccine Name: IL-12p70
- Target Pathogen: Cancer
- Target Disease: Cancer
- Vaccine Ontology ID: VO_0007621
- Type: Dendritic Cell Vaccine
- Status: Clinical trial
- Antigen: gp100
- Preparation: 7 HLA-A*0201+ newly diagnosed stage IV melanoma patients were immunized against the gp100 melanoma antigen using autologous peptide-pulsed, CD40L/IFN-γ-matured DCs (Carreno et al., 2013).
- Immunization Route: Intramuscular injection (i.m.)
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| Host Response |
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| References |
Carreno et al., 2013: Carreno BM, Becker-Hapak M, Huang A, Chan M, Alyasiry A, Lie WR, Aft RL, Cornelius LA, Trinkaus KM, Linette GP. IL-12p70-producing patient DC vaccine elicits Tc1-polarized immunity. The Journal of clinical investigation. 2013; 123(8); 3383-3394. [PubMed: 23867552].
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