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Vaccine Detail

Corynebacterium parvum, DTIC
Vaccine Information
  • Vaccine Name: Corynebacterium parvum, DTIC
  • Target Pathogen: Cancer
  • Target Disease: Cancer
  • Type: bacterial cell
  • Status: Research
  • Preparation: Nonspecific immunotherapy with monthly intramuscular (IM) injections (Clunie et al., 1980).
  • Immunization Route: Intramuscular injection (i.m.)
Host Response

Human Response

  • Vaccine Immune Response Type: VO_0003057
  • Immune Response: a fall in T-cell counts and a rise in anti-C parvum antibodies were seen in patients receiving C parvum, but these changes did not reach the 5% level of significance when compared with the group undergoing chemotherapy alone (Clunie et al., 1980).
References
Clunie et al., 1980: Clunie GJ, Gough IR, Dury M, Furnival CM, Bolton PM. A trial of imidazole carboxamide and corynebacterium parvum in disseminated melanoma: clinical and immunologic results. Cancer. 1980; 46(3); 475-479. [PubMed: 6994866].