• Vaccine Name: hapten dinitrophenyl
• Target Pathogen: Cancer
• Target Disease: Cancer
• Vaccine Ontology ID: VO_0007611
• Type: DNP vaccine
• Status: Research
• Immunization Route: Intramuscular injection (i.m.)
• Description: Postsurgical adjuvant therapy with autologous DNP-modified vaccine appears to produce survival rates that are markedly higher than have been reported with surgery alone. Moreover, this approach has some intriguing immunobiologic features that might provide insights into the human tumor-host relationship (Berd et al., 1997).

Human Response

• Vaccine Immune Response Type: VO_0003057
• Immune Response: These experiments thus demonstrated that patients immunized with the g209-2M synthetic peptide in IFA consistently developed high levels of circulating immune precursors reactive with the native g209–217 peptide and with tumor (Berd et al., 1997).