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Vaccine Detail
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Synchotrope TA2M Vaccine |
| Vaccine Information |
- Vaccine Name: Synchotrope TA2M Vaccine
- Target Pathogen: Cancer
- Target Disease: Cancer
- Vaccine Ontology ID: VO_0007108
- Type: Recombinant plasmid DNA vaccine
- Status: Research
- Immunization Route: Intramuscular injection (i.m.)
- Description: This is for Melanoma Cancer (NCT00023647). A recombinant plasmid DNA vaccine that encodes two peptides, tyrosinase 207–216 and tyrosinase 1–17, both of which are derived from human tyrosinase (Tagawa et al., 2003).
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| Host Response |
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Human Response
- Vaccine Immune Response Type: VO_0003057
- Immune Response: There were no or minimal responses to the epitopes tyrosinase 1–9 and tyrosinase 8 –17 by tetramer assay (Tagawa et al., 2003).
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| References |
NCT00023647: [https://clinicaltrials.gov/show/NCT00023647]
Tagawa et al., 2003: Tagawa ST, Lee P, Snively J, Boswell W, Ounpraseuth S, Lee S, Hickingbottom B, Smith J, Johnson D, Weber JS. Phase I study of intranodal delivery of a plasmid DNA vaccine for patients with Stage IV melanoma. Cancer. 2003; 98(1); 144-154. [PubMed: 12833467].
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