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Vaccine Detail
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DNP-modified autologous vaccine |
| Vaccine Information |
- Vaccine Name: DNP-modified autologous vaccine
- Target Pathogen: Cancer
- Target Disease: Cancer
- Vaccine Ontology ID: VO_0007601
- Type: DNP-modified autologous vaccine
- Status: Research
- Immunization Route: Intramuscular injection (i.m.)
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| Host Response |
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Human Response
- Vaccine Immune Response Type: VO_0003057
- Immune Response: Out of the 12 responding patients in the present series, 11 had developed a strong positive DTH response to their autologous tumour cells. The relatively high response rates we have witnessed when IL-2 was given following immunisation suggests that the whole tumour vaccine may have generated tumour-reactive T-cell subsets. Interleukin-2 was probably required to turn these precursors into effector cells (Lotem et al., 2004).
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| References |
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