• Vaccine Name: Hantavirus DNA vaccine pWRG/HTN-M
• Target Pathogen: Hantavirus
• Target Disease: Hantavirus Pulmonary Syndrome
• Vaccine Ontology ID: VO_0004576
• Type: DNA vaccine
• Status: Research
• Host Species as Laboratory Animal Model: Hamsters
• GP gene engineering:
  • Type: DNA vaccine construction
  • Description:
  • Detailed Gene Information: Click Here.
• DNA vaccine plasmid:
  • DNA vaccine plasmid name:
  • DNA vaccine plasmid VO ID: VO_0000346
• Immunization Route: Gene gun

Hamster Response

• Vaccine Immune Response Type: VO_0003057
• Efficacy: All of the hamsters that were vaccinated with pWRG/HTN-M were protected against infection as defined by an absence of a postchallenge N-specific antibody response. In addition, the pre- and postchallenge PRNT titers differed by ≤4-fold. In contrast, all of the negative control hamsters, whether they were vaccinated with pWRG7077 or remained unvaccinated, were infected, as evidenced by the development of N-specific antibodies and neutralizing antibodies postchallenge (Hooper et al., 2001).