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Vaccine Detail
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Duck hepatitis virus 1 DNA vaccine pSCA/VP1 |
| Vaccine Information |
- Vaccine Name: Duck hepatitis virus 1 DNA vaccine pSCA/VP1
- Target Pathogen: Duck hepatitis virus 1
- Target Disease: Duck virus hepatitis (DVH)
- Vaccine Ontology ID: VO_0004575
- Type: DNA vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Ducklings
- VP1
gene engineering:
- Type: DNA vaccine construction
- Description:
- Detailed Gene Information: Click Here.
- DNA vaccine plasmid:
- DNA vaccine plasmid name:
- DNA vaccine plasmid VO ID: VO_0001000
- Immunization Route: Intramuscular injection (i.m.)
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| Host Response |
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Ducks Response
- Vaccine Immune Response Type: VO_0003057
- Immune Response: DHV-1-specific antibodies, neutralizing antibodies and lymphocyte proliferation were well induced in ducklings (Fu et al., 2012).
- Efficacy: Vaccination with pSCA/VP1 could significantly reduce the onset and duration of viremia and decrease virus replication in ducklings (Fu et al., 2012).
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| References |
Fu et al., 2012: Fu Y, Chen Z, Li C, Liu G. Protective immune responses in ducklings induced by a suicidal DNA vaccine of the VP1 gene of duck hepatitis virus type 1. Veterinary microbiology. 2012; 160(3-4); 314-318. [PubMed: 22819169].
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