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Vaccine Detail
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Influenza virus DNA vaccine pCMVH5HA |
| Vaccine Information |
- Vaccine Name: Influenza virus DNA vaccine pCMVH5HA
- Target Pathogen: Influenza virus
- Target Disease: Influenza (flu)
- Vaccine Ontology ID: VO_0004500
- Type: DNA vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Chicken
- HA
gene engineering:
- Type: DNA vaccine construction
- Description: Vector pCMV expressed a full-length cDNA copy of the HA gene of Ty/Ire/83 (Kodihalli et al., 2000).
- Detailed Gene Information: Click Here.
- DNA vaccine plasmid: pCMV DNA vaccine plasmid
- Immunization Route: Gene gun
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| Host Response |
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Chicken Response
- Vaccine Immune Response Type: VO_0000286
- Efficacy: Chickens given a single dose of plasmids expressing H5 and H7 hemagglutinins protected the birds from infection by either subtype (Kodihalli et al., 2000).
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| References |
Kodihalli et al., 2000: Kodihalli S, Kobasa DL, Webster RG. Strategies for inducing protection against avian influenza A virus subtypes with DNA vaccines. Vaccine. 2000; 18(23); 2592-2599. [PubMed: 10775793].
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