• Vaccine Name: VEE virus DNA vaccine encoding 26S
• Target Pathogen: VEE Virus
• Target Disease: Venezuelan equine encephalitis
• Vaccine Ontology ID: VO_0004488
• Type: DNA vaccine
• Status: Research
• Host Species as Laboratory Animal Model: Mouse
• 26S mRNA gene engineering:
  • Type: DNA vaccine construction
  • Description: Vector pWRG7077 expressed VEEV 26S gene (Riemenschneider et al., 2003).
  • Detailed Gene Information: Click Here.
• DNA vaccine plasmid:
  • DNA vaccine plasmid name:
  • DNA vaccine plasmid VO ID: VO_0000346
• Immunization Route: Intramuscular injection (i.m.)

Mouse Response

• Vaccine Immune Response Type: VO_0000286
• Efficacy: DNA vaccines to four dissimilar pathogens that are known biowarfare agents, Bacillus anthracis, Ebola (EBOV), Marburg (MARV), and Venezuelan equine encephalitis virus (VEEV), can elicit protective immunity in relevant animal models. In addition, a combination of all four vaccines is shown to be equally as effective as the individual vaccines for eliciting immune responses in a single animal species (Riemenschneider et al., 2003).