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Vaccine Detail
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Vaccinia virus DNA vaccine A33R from strain IHD-J |
| Vaccine Information |
- Vaccine Name: Vaccinia virus DNA vaccine A33R from strain IHD-J
- Target Pathogen: Vaccinia virus
- Vaccine Ontology ID: VO_0004482
- Type: DNA vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Mouse
- A33R
gene engineering:
- Type: DNA vaccine construction
- Description: Vector pCI (Promega) expressed the extraviral domains of A33R (Galmiche et al., 1999).
- Detailed Gene Information: Click Here.
- DNA vaccine plasmid:
- DNA vaccine plasmid name:
- DNA vaccine plasmid VO ID: VO_0000212
- Immunization Route: Intramuscular injection (i.m.)
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| Host Response |
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Mouse Response
- Vaccine Immune Response Type: VO_0000286
- Efficacy: Vaccination with A33R protein also provided protection, resulting in a 100% survival rate and in a significantly lower body weight loss and a more rapid recovery from infection than with B5R protein (Galmiche et al., 1999).
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| References |
Galmiche et al., 1999: Galmiche MC, Goenaga J, Wittek R, Rindisbacher L. Neutralizing and protective antibodies directed against vaccinia virus envelope antigens. Virology. 1999; 254(1); 71-80. [PubMed: 9927575].
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